Sleep Architecture & Cognition in Focal Epilepsy
University of California, Davis
Summary
Focal Epilepsy (FE) patients and healthy controls will wear an actigraph at home for one week and a home sleep study device at home for one night. Participants will then undergo two nights of testing (at least one week apart) at California Sleep Solutions (CSS) in Sacramento, CA. During the overnight stays, participants will have EEG leads placed and possibly a headband. They will undergo cognitive testing before they go to sleep and again in the morning. During one night of testing, sounds will be played in the room (acoustic stimulation). The sounds should not wake the participants.
Description
This study will investigate the interconnections between sleep physiology and cognitive deficits in FE and will provide essential pilot data for an interventional trial to characterize the comprehensive effects of AS/ES on sleep and cognition in FE. The long-term goal of this project is to leverage the connections between sleep, behavior, and neural network activity to develop and implement tailored cognitive and sleep interventions for individuals with epilepsy. AIM 1: Characterize sleep architecture patterns in Focal Epilepsy (FE) and determine the relationship to cognitive processing. AIM…
Eligibility
- Age range
- 18–40 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Age 18 - 40 years of age * Focal Epilepsy * Capacity to fully cooperate and follow directions * no other significant neurological disorders which could affect cognition Exclusion Criteria: * Current use of any medications that can significantly affect cognition * No severe sleep apnea
Interventions
- OtherAcoustic Stimulation (AS)
Acoustic Stimulation will be administered while participants have their sleep monitored.
- OtherSHAM Stimulation
No stimulation will be administered while participants have their sleep monitored.
Location
- UC DavisSacramento, California