A Multilevel Intervention to Personalize and Improve Tobacco Treatment in Primary Care (MOTIVATE)
Washington University School of Medicine
Summary
This study examines the application of precision treatment intervention for smoking cessation from both the clinician perspective and patient perspective, and compares it to usual care on tobacco treatment in the primary care setting. The precision treatment intervention includes personalized tobacco treatment recommendations using the patient's clinical, genetic, and biomarker information. This approach may increase effectiveness and adherence for the patient, and increase the clinician's likelihood of prescribing.
Description
The overarching goal of this study is to test the impact of a multilevel precision treatment intervention aiming to address gaps in clinician and patient uptake of tobacco treatment and overall treatment effectiveness. This study builds on evidence that (1) genetic and metabolic factors may inform precision tobacco treatment and (2) increasingly high demand for precision treatment, in particular, may signal its potential to activate behavior change. The multilevel precision treatment intervention to be tested--PrecisionTx-- provides the opportunity to present personalized risk, benefit, and tr…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Eligibility Criteria for Primary and Specialty Care Clinicians * Clinician from participating clinic * At least 18 years of age * Can speak and understand English Eligibility Criteria for Primary Care and Specialty Patients Inclusion: * Patient at participating clinic * Age 18 years or older, inclusive * Current smoking (cigarettes per day \>=5) * Can speak and understand English * Willing to consider medication to help reduce craving or smoking such as nicotine patch, lozenge, or varenicline Exclusion: * Active use of smoking cessation medication (within the past 30 days) * Receipt of s…
Interventions
- BehavioralPrecision Treatment
Precision treatment will be informed by practice guidelines (standard of care, brief advice, and guideline awareness), plus patient-specific risk feedback and personalized tobacco treatment recommendations using patients' clinical, genetic, and biomarker information.
- BehavioralUsual Care
Usual care will be informed by practice guidelines (standard of care, brief advice, and guideline awareness).
Location
- Washington University School of MedicineSt Louis, Missouri