Tympanoseal (Tympanic Membrane Device) Clinical Study
Grace Medical, Inc.
Summary
The purpose of this investigational study is to assess the ability of Tympanoseal (sodium/calcium alginate), an investigational device, to act as a scaffold during healing of the tympanic membrane. Tympanoseal is intended for use following removal or extrusion of indwelling tympanostomy tubes or traumatic injury of the tympanic membrane.
Description
This study will provide data on the safety and the ability of sodium/calcium alginate gels to act as a scaffold capable of occluding a tympanic membrane perforation over the duration of complete healing. Tympanoseal could be used in cases where cartilage or fat graft tympanoplasty would be indicated.
Eligibility
- Age range
- 2–100 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: 1. Male or female patients over 2 years of age at enrollment 2. Documentation of a retained tympanostomy tube or perforation less than 5 mm not on the edge of the tympanic membrane. 3. Written informed consent (and assent when applicable) obtained from subject or subject's legal guardian and ability for subject to comply with the requirements of the study Exclusion Criteria: 1. Active otorrhea or otitis media 2. Otorrhea or otitis media within 4 weeks prior to the operation 3. History of cholesteatoma 4. Perforations on the edge of the tympanic membrane 5. Presence of a…
Interventions
- DeviceTympanoseal
All subjects will receive the Tympanoseal device that will be placed during a surgical procedure
Locations (2)
- Michigan Ear InstituteFarmington Hills, Michigan
- Methodist Le BonheurMemphis, Tennessee