Prospective Evaluation of the Effect of Opioid Cessation on Opioid-Induced Esophageal Dysfunction (OIED)
Mayo Clinic
Summary
The purpose of this study is to evaluate the effect of opioid cessation on opioid-induced esophageal dysfunction (OIED).
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: \- Patients enrolled in the Pain Rehabilitation Center for opioid cessation, with or without esophageal symptoms. Exclusion Criteria: * Inability to provide informed consent. * Patients with previous gastroesophageal surgery or pneumatic dilation. * Esophageal botulinum toxin injection within the prior 12 months. * Esophageal stricture * Achalasia types I and II * Allergy to Lidocaine or other local anesthetics * Subjects on anticoagulation * Bilateral nasal obstruction * Pregnancy or breast feeding
Interventions
- BehavioralOpioid cessation
opioid cessation will occur during pain rehabilitative program over approximately 3 weeks
- OtherNo opioid cessation
Subjects will not stop taking opioids
Location
- Mayo Clinic MinnesotaRochester, Minnesota