HeartShare Deep Phenotyping Study
Northwestern University
Summary
HeartShare is a comprehensive study of heart failure, a common and serious medical condition which occurs when the heart is unable to keep up with the demands of the body, resulting in shortness of breath, fluid retention, and fatigue. HeartShare aims to better classify heart failure into subtypes to help develop more personalized treatments for patients, with the hope that this will improve the lives of heart failure patients. To do this, HeartShare is bringing together a large amount of data (including images, such as heart ultrasounds and MRIs and molecular data from the blood, such as genetics) from previously conducted studies and electronic health records, and is gathering new data through participants enrolled in the HeartShare Deep Phenotyping Study.
Eligibility
- Age range
- 30+ years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: HF Inclusion Criteria (HeartShare Registry) 1. Age ≥30 years. 2. Prior diagnosis of HF in the EHR (any left ventricular ejection fraction). Non-HF Group Inclusion Criteria (HeartShare Registry) 1. Age ≥30 years. 2. No known prior diagnosis of HF or use of loop diuretics. 3. No known prior history of BNP \>100 pg/ml or NTproBNP \>300 pg/ml, if prior laboratory tests are available in the EHR. HFpEF Inclusion Criteria (HeartShare Deep Phenotyping Cohort) 1. Age ≥30 years. 2. Left ventricular ejection fraction ≥50% measured by echocardiography. 3. Definition of HFpEF: sig…
Locations (6)
- University of California DavisSacramento, California
- Northwestern UniversityChicago, Illinois
- Mass General BrighamBoston, Massachusetts
- Mayo ClinicRochester, Minnesota
- Wake Forest UniversityWinston-Salem, North Carolina
- University of PennsylvaniaPhiladelphia, Pennsylvania