Reducing AIR Pollution Exposure to Lower Blood PRESSURE Among New York City Public Housing Residents
NYU Langone Health
Summary
Fine particulate matter \<2.5 µm (PM2.5) air pollution is the fifth leading risk factor for global mortality, with the largest portion of deaths due to cardiovascular disease (CVD). While several mechanisms are responsible, PM2.5-induced elevations in blood pressure (BP) may be relevant. Indoor portable air cleaners (PACs) are a novel approach to reduce exposure to PM2.5 and potentially lower blood pressure. The current study is being conducted to provide evidence that PACs reduce PM2.5 exposure and lower systolic blood pressure (SBP) in key patient populations.
Eligibility
- Age range
- 18–100 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * self-reported nonsmokers living in a nonsmoking household. * adults living with hypertension (HTN) from NYC public housing. Exclusion Criteria: * History of major known arrhythmias (e.g. atrial flutter or fibrillation, ventricular tachycardia). * Screening systolic BP ≥160 mm Hg or diastolic BP ≥100 mm Hg (i.e. severe hypertension by the 2017 ACC/AHA BP guideline). * A change in drug regimen in the prior 2 weeks or a planned change in drug regimen during the first 30 days for those taking antihypertensive medication. * Current smoking or living with an active smoker wh…
Interventions
- DeviceActive PAC
The active PAC will contain HEPA filters inside the device.
- DeviceSham PAC
The sham PAC will contain no HEPA filters inside the device.
Location
- NYU Langone HealthNew York, New York