Magnetic Resonance Imaging in RadiotheRapy fOr bReast Cancer (MIRROR): A Pilot Study of MRI Simulation
University of California, San Francisco
Summary
This is a single-center, prospective pilot study evaluating feasibility and efficacy of incorporating magnetic resonance imaging (MRI) simulation into the planning of radiation treatment (RT) for breast cancer.
Description
PRIMARY OBJECTIVE: I. To determine feasibility of acquiring MRI simulation prior to RT planning. EXPLORATORY OBJECTIVE: I. To determine change in target volume with MRI simulation compared to Computerized tomography (CT) simulation. OUTLINE: MRI simulation will be performed once at baseline. There is no follow up planned for study purposes. Patients will be followed as part of their regular clinical care.
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: 1. Participants with an Eastern Cooperative Oncology Group (ECOG) performance status \<=2 (or Karnofsky ≥\>=60%, see Appendix A). 2. Participants with the ability to understand and the willingness to sign a written informed consent document. 3. Participants may separately enroll on therapeutic clinical trials when they enroll on this trial. Note: All interventions on this protocol are standard of care, so enrollment on other therapeutic protocols is allowed at the discretion of the treating physician. 4. Patients must have pathologically confirmed invasive or in situ breas…
Interventions
- Diagnostic TestMagnetic Resonance Imaging Simulation
Radiographic Image Simulation
Location
- University of California, San FranciscoSan Francisco, California