Profile-Related Evidence Determining Individualized Cancer Therapy in Pancreatic Cancer (PREDICT-PANC)
Medical College of Wisconsin
Summary
This is a non-therapeutic exploratory observational precision oncology study designed to collect and analyze data that demonstrate the clinical efficacy and tolerability of personalized treatments based on molecular tumor profiling assessments (i.e., matched therapy) in adult pancreatic cancer patients. Patient medical records, obtained both retrospectively and prospectively, will be examined for results of molecular profiling obtained through standard of care testing to help understand how well molecular testing might predicts response to therapy. Patient demographic and outcome parameters to be evaluated include, but are not limited to, tumor response, time to treatment failure, patient survival, and toxicity.
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Age ≥18 years. * Pathologically confirmed pancreatic cancer. * Ability to understand a written informed consent document and the willingness to sign it Exclusion Criteria: * Age \<18 years. * Primary cancer diagnosis other than pancreatic cancer.
Interventions
- OtherTargeted Therapy
Approved interventions based on the subject's genomic profile will be provided to investigators for consideration for anti-tumor therapy.
Location
- Froedtert Hospital and the Medical College of WisconsinMilwaukee, Wisconsin