The Impact of a Culturally-based Live Music Intervention on the Metabolites and Metabolic Pathways Associated With Chronic Stress and the Risk of Pre-term Birth in Black Women
Columbia University
Summary
This study will test a music intervention (MI) versus a sham control (SC) arm which only includes a verbal intervention, to determine if the effects of the music intervention will reduce the biological impact of chronic stress among pregnant Black women, reduce preterm birth, and improve infant outcomes.
Description
Preterm birth occurs at unacceptably high rates in the United States, with Black women disproportionately affected. A long-recognized risk factor for preterm birth in this population is the relentless exposure to intersectional stress related to racial and sexual discrimination, poverty, and neighborhood disadvantage that Black women often experience from an early age. In this interdisciplinary study, the investigators bring together experts in preterm birth, music therapy, and metabolomics to address this health disparity by testing the efficacy of a live, culturally based music intervention…
Eligibility
- Age range
- 18–40 years
- Sex
- Female
- Healthy volunteers
- No
Inclusion Criteria * Aged 18 to 40 years * Generally healthy pregnant women in the first trimester of pregnancy Exclusion Criteria: * Non-pregnant women * Women with a chronic medical condition that could impact pregnancy health or duration * Women regularly taking any medications other than prenatal vitamins
Interventions
- BehavioralMusic Intervention (MI)
The intervention will involve listening, playing and/or singing melodies or songs, that are meaningful to the participant, with interpretation/reflection on their relevance/capacity to alter stress.
- OtherSham Control (SC)
The intervention will be to support a woman to talk about anything she wants that is important to her.
Locations (2)
- Louis Armstrong Center for Music and Medicine at Mount Sinai Health SystemNew York, New York
- Columbia University Irving Medical Center/NewYork PresbyterianNew York, New York