Thibang Diphatlha: Testing Adaptive Strategies to Close the Gap From Cervical Cancer Diagnosis to Treatment in Botswana
Abramson Cancer Center at Penn Medicine
Summary
Investigators will test the effectiveness of adaptive strategies on timely adoption of cervical cancer treatment in Botswana using a pragmatic trial design.
Description
Investigators will test the effectiveness of adaptive strategies on timely adoption of cervical cancer treatment in Botswana using a hybrid (type III) and pragmatic Sequential Multiple Assignment Randomized Trial (SMART) design. The adaptive strategies are designed to target patient- and system-level determinants identified in preliminary data, including delayed communication of results, individual and structural barriers to accessing treatment, and suboptimal care coordination between referring and cancer treatment clinics. The strategies draw upon key principles in behavioral economics and a…
Eligibility
- Age range
- 18+ years
- Sex
- Female
- Healthy volunteers
- No
Inclusion Criteria: Patients will be eligible if they: 1. are biological females 2. are aged 18 or older 3. have pathology-confirmed invasive cervical cancer diagnosis 4. have pathology results evaluated at National Health Laboratory in Botswana 5. are citizens of Botswana 6. have no prior history of invasive cervical cancer Exclusion Criteria: Patients will be excluded if they: 1. are biological males or otherwise born without a cervix 2. are below the age of 18 due to the rarity of cervical cancer in this population 3. do not meet study inclusion criteria
Interventions
- BehavioralClinic Outreach
A member of the pathology team will contact the referring clinic to communicate the readiness of results.
- BehavioralEnhanced Outreach
A member of the pathology team will contact both the referring clinic and the patient directly to communicate the readiness of results.
- BehavioralLow-Touch Strategy
Patient will be sent asynchronous text messaging reminders related to the importance of timely care using framed messaging.
- BehavioralHigh-Touch Strategy
Patient will be sent asynchronous text messaging reminders related to the importance of timely care using framed messaging in combination with synchronous telephone-based patient navigation.
Locations (3)
- University of PennsylvaniaPhiladelphia, Pennsylvania
- Nyangabgwe Referral HospitalFrancistown, North-East District
- Princess Marina HospitalGaborone