Neural Prediction to Enhance Language Outcomes in Children With Cochlear Implant
Ann & Robert H Lurie Children's Hospital of Chicago
Summary
The language outcome of children receiving cochlear implantation to address bilateral sensorineural hearing loss is more variable than that of typical hearing children. The research is focused upon development of neural predictive models based upon brain imaging to forecast language after cochlear implantation on the individual child level. The long-term goal is improving children's language by using predictive models to enable a custom "predict to prescribe" approach to intervene with more effective behavioral therapy for children at risk to develop poorer language. The investigators previously developed models for short term language outcome of English-learning implanted children. The aims of this study are to 1. Develop models able to predict long term outcome for English- learning and Spanish-learning children; and 2. To evaluate whether English-learning children predicted to achieve lower language based on the investigators' previously constructed models can demonstrate significant gains from Parent Implemented Communication Treatment (PICT). PICT is an intensive parent education program about strategies to improve children's communication.
Description
Arm1: Non-treatment Model Building. Up to 700 children will be recruited from 5 cochlear implant programs in the United States. Children will be enrolled and followed for up to four years after implantation. Study information will be obtained from each child's medical record before and after implantation including cause of hearing loss, general health, language and communication history, family history, cochlear implant device and surgery. Audiological information before and after implantation will be collected from routine visits that are part of cochlear implant candidacy evaluation and audi…
Eligibility
- Age range
- 0–5 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria (Arm 1): 1. Children with sensorineural hearing loss who meet clinical criteria for cochlear implantation in both ears who meet the following age criteria at time cochlear implant evaluation begins: * Age 5 years and under. * English or Spanish as the dominant language. 2. English or Spanish dominant language in the home. Inclusion Criteria (Arm 2): 1. Children with bilateral sensorineural hearing loss who meet clinical criterial for cochlear implantation 2. English dominant spoken language by family 3. Age at implantation of 36 months and younger when treatment be…
Interventions
- BehavioralParent-Implemented Communication Treatment
The intervention will be taught by a qualified professional online and/or in-person for about 6 months. Parents will learn strategies to enhance their children's social communication and will receive coaching and feedback.
Location
- Ann & Robert H. Lurie Children's Hospital of ChicagoChicago, Illinois