Microendoscopic Electrical Impedance Sensing for Real-time Intraoperative Surgical Margin Assessment
Ryan J. Halter
Summary
This research will study a custom device developed to detect if any prostate cancer tissue is left behind when the prostate is removed. This device is called an Electrical Impedance Imaging (EII) probe.
Description
Two hundred men will be recruited to participate in this trial. Consent will be obtained from all participating men prior to surgery. The trial will consist of recording EII data from: 1. In vivo pelvic floor and peri-prostatic tissues remaining after the prostate has been resected 2. Resected ex vivo prostate following extraction from the abdomen (in the OR) 3. Resected ex vivo prostate when transferred to Pathology, post-RARP The study team will also track post-surgical complications due to the study's technology (e.g., infection) and additional time required to deploy the study technolog…
Eligibility
- Age range
- 18+ years
- Sex
- Male
- Healthy volunteers
- No
Inclusion Criteria: 1. Clinical diagnosis of prostate cancer requiring RARP. 2. Ability to understand and the willingness to sign a written informed consent document. 3. Age ≥ 18 years old Exclusion Criteria: 1. Adults with implanted electrical devices such as pacemakers 2. Prisoners 3. Adults with impaired decision-making capacity 4. Any condition for which, in the opinion of the investigator, contraindicates study participation.
Interventions
- Devicecustom device to demonstrate a significant difference in electrical impedance signatures
Custom device will be used to measure electrical impedance signatures.
Location
- Dartmouth-Hitchcock Medical CenterLebanon, New Hampshire