Medical College of Wisconsin
This study will assess the effects of transcranial alternating current stimulation (tACS) on language recovery after stroke.
Aphasia is a debilitating disorder, typically resulting from damage to the left hemisphere, that can impair a range of communication abilities, including language production and comprehension, reading, and writing. Approximately 180,000 new cases of aphasia are identified per year, and approximately 1 million or 1 in 250 are living with aphasia in the United States. Treatments are limited and provide modest benefits at best. The current emphasis in aphasia rehabilitation is to formulate intensive speech and language therapies and augment therapeutic benefits, potentially with brain stimulation…
Inclusion Criteria: * Diagnosed with left hemisphere stroke/aphasia * Consent date \>= 1 month after stroke onset * Fluent in English * 18 years of age or older Exclusion Criteria: * Severe cognitive, auditory or visual impairments that would preclude cognitive and language testing * Presence of major untreated or unstable psychiatric disease * A chronic medical condition that is not treated or is unstable * The presence of cardiac stimulators or pacemakers * Contraindications to MRI or tACS, e.g. patients with metallic implants, and/or history of skull fractures, pregnancy, skin diseases *…
High definition tACS will be applied during speech therapy.
Sham high definition tACS will be applied during speech therapy.
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