A Healthy Weight Intervention for Family Stress During the Early Phases of ALL Treatment: NOURISH-ALL
University of Kansas Medical Center
Summary
The purpose of this study is to conduct a single arm pilot of the NOURISH-ALL (Nourishing Our Understanding of Role modeling to Improve Support and Health in Acute Lymphoblastic Leukemia) intervention focused on three components of participant engagement. This is a single arm intervention study that involves participation in a 6-session family intervention and three time points of multimethod data collection. The primary outcome is participant engagement, measured as recruitment, retention, and intended dose received. This study will be conducted over 5 years in three phases: * Aim 1a: Adapting the NOURISH-ALL Intervention for Families of Youth with ALL (Year 1) * Aim 1b: Iteratively Refining the NOURISH-ALL Intervention (Year 2) * Aim 2: Pilot Single-Arm Trial of NOURISH-ALL Focused on Participant Engagement (Years 3-5)
Description
The long-term goal of this work is to establish an efficacious family-based health promotion intervention that curbs excessive weight gain among youth with newly diagnosed acute lymphoblastic leukemia (ALL) by integrating support for family coping with stress during the early phases of treatment. The objectives of the current study are to adapt an existing family-based health promotion intervention, NOURISH-T, to meet the needs of families of youth in the early phases of ALL treatment (NOURISH-ALL) and (2) assess three key components of engagement in preparation for a fully powered efficacy t…
Eligibility
- Age range
- 2–12 years
- Sex
- All
- Healthy volunteers
- Not specified
Inclusion Criteria: * Children ages 2-12 years old and their primary caregiver ages 18-90 * Child diagnosed with acute lymphoblastic leukemia (ALL) * Child completed induction phase of therapy and not yet in maintenance phase of therapy * Primary caregiver and child English language proficient * Primary caregiver able to provide permission for child to participate in research * Primary caregiver identifies as being involved with child's oncology care * Primary caregiver lives with child at least 50% of the time * Primary oncology provider confirms child is eligible to participate Exclusion C…
Interventions
- BehavioralNOURISH-ALL
Our NOURISH-ALL intervention will build on this existing NOURISH-T family based behavioral intervention with families of cancer survivors. The intervention, NOURISH-ALL, will adapt these family-based health promotion strategies to the early ALL treatment context.
Locations (2)
- University of Kansas Medical CenterKansas City, Kansas
- Children's Mercy Kansas CityKansas City, Missouri