Neurodegeneration and Neuronal Fluctuations in Lewy Body Disease and Alzheimer Disease
Mayo Clinic
Summary
The purpose of this research study is to investigate how the brain, memory, thinking, and motor behavior change both in individuals with movement and/or cognitive disorders, as well as healthy individuals. Researchers will look at measurements of memory, thinking, brain wave and muscle activity, daily functioning, and brain scans to learn more about brain disorders such as Alzheimer disease and Lewy body disease.
Eligibility
- Age range
- 50–95 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Use English as their primary language. * Be willing to undergo health and cognitive assessments, as well as brain MRI and EEG study. * Will be encouraged to have an available study partner (also called a "co-participant") who is familiar with the participant's daily functioning. * This study will be limited to healthy individuals, and patients who have a clinical diagnosis made by a board-certified neurologist of Lewy body disease or Alzheimer disease. * All individuals must be capable of providing informed consent and complying with the trial procedures. Realizing the c…
Interventions
- Diagnostic TestMagnetic Resonance Imaging
Test that looks at the structure of the brain.
- Diagnostic TestElectroencephalography
Non-invasive technique to measure brain waves
- Diagnostic TestElectromyography
Technique to evaluate muscle activity
Location
- Mayo Clinic ArizonaScottsdale, Arizona