University of Pittsburgh
This controlled clinical trial will assess clinically, immunologically, and microbiologically the healing of experimental peri-implant mucositis (PIM) lesions in implants treated previously with implantoplasty (IP) compared to those treated without IP.
The present parallel controlled clinical trial is designed as a 21-day experimental peri-implant mucositis, followed by a period of resolution of 21 days in healthy implants that were previously treated for peri-implantitis with and without implantoplasty. A total of 8 appointments over the course of about 42 days will be necessary. These appointments will take place in the Department of Periodontics \& Preventive Dentistry and are described as follows: Screening Appointment (14 days prior to Day 0): During this visit, informed consent will be obtained from each subject and inclusion criteri…
Inclusion Criteria: * Aged 18-80 years * In good general health, (at least ASA 2) * Previously treated implants must have probing depths (PD) ≤ 4 mm * Previously treated implants must have \<50% bone loss around the implant of interest (assessed radiographically) * Patients must have been treated previously for peri-implantitis with or without IP, with at least 1 thread or 2 mm of implant surface exposed in the oral cavity. * Have little to no bacteria on the implant(s) of interest (modified Plaque Index of \<1) by Day 0 * Have healthy gums that do not bleed around the implant(s) of choice (m…
Patients will refrain from oral hygiene measures at the implant sites for 3 weeks to induce peri-implant mucositis, by using a stent in the included implant during oral hygiene.
Patients will reinstitute oral hygiene measures, receive an oral prophylaxis and oral hygiene instructions and will be evaluated during 3 weeks.
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