EXERT-BCH: Prospective Study of EXErcise Regimens After Treatment for Breast Cancer to Improve Hypertrophy
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Summary
The purpose of this research study is to evaluate the outcomes of two standard of care group exercise regimens to increase muscle mass in women who have been treated with breast cancer.
Description
This protocol seeks to analyze patient outcomes of two standard of care, time-efficient, monitored group exercise regimens of high-load resistance training to improve hypertrophy in women who have been treated for ductal carcinoma in situ or invasive carcinoma of the breast. As part of the standard exercise program, patients will undergo a fitness evaluation at the AHNCI Exercise Oncology and Resiliency Center before the start of the exercise program. This evaluation will be used to customize the patient exercise program. The exercise program consists of small group training sessions held app…
Eligibility
- Age range
- 20–89 years
- Sex
- Female
- Healthy volunteers
- No
Inclusion Criteria: Age 20-89 years * Women with a biopsy proven diagnosis of ductal carcinoma in situ or invasive carcinoma of the breast * Women must have undergone treatment for breast cancer, including one or more of the following: surgery, radiation therapy, chemotherapy, immunotherapy, or hormonal therapy. Women undergoing active chemotherapy are not allowed on study. Immunotherapy or targeted agent usage is allowed. Exclusion Criteria: * Any current treatment with cytotoxic chemotherapy for breast cancer * Inability to safely engage in group sessions of resistance training as deemed…
Interventions
- OtherControl Arm ACSM Guidelines
The control group will follow resistance training guidelines from the American College of Sports Medicine. Eight to ten multi-joint exercises will be performed to stress the major muscle groups.
- OtherExperimental Arm 6-12-25 repetitions per set
The exercise regimens will employ a mixture of compound exercises utilizing both open and closed kinetic chain movements (CKC), focusing on exercises with the goal of increasing skeletal muscle mass and body composition. The regimen will incorporate 6, then 12, then 25 repetitions in sequence per set per muscle group with minimal amounts of rest between.
Location
- Allegheny General HospitalPittsburgh, Pennsylvania