Prospective Assessment of HPV Associated Anogenital Pathology in Female Patients and Female Partners of Patients With Confirmed HPV Associated Oropharyngeal Carcinoma (PAP-OP)
Mayo Clinic
Summary
This study evaluates how often women with throat (oropharyngeal) cancer or who have a partner with oropharyngeal cancer get anogenital infections with high risk, potentially cancer-causing types of human papilloma virus (HPV).
Description
PRIMARY OBJECTIVES: I. Prospectively determine the incidence of anogenital infection with high-risk HPV serotypes and HPV-associated anogenital lesions in female patients with newly diagnosed HPV(+)OPSCC and female partners of patients with HPV(+)OPSCC, and compare this with retrospective review of exams and paps obtained during routine well woman checks in Rochester MN. II. To determine the risk of requiring additional procedures or treatments secondary to these diagnoses. III. To determine the sexual health and well-being among patients and partners with HPV(+)OPSCC. IV. To develop stand…
Eligibility
- Age range
- 18+ years
- Sex
- Female
- Healthy volunteers
- Yes
Inclusion Criteria: * \* Female patients with diagnosed HPV(+)OPSCC seen at the Mayo Clinic, Rochester * Age ≥ 18 * Female partners of Mayo Clinic patients with diagnosed HPV(+)OPSCC * Patient has given permission to give his/her blood/saliva sample for research testing * Ability to complete questionnaire(s) by themselves or with assistance Exclusion Criteria: * \* HPV(-) OPSCC * Unable to provide informed consent * Unwilling to attend screening visit at Mayo Clinic site, if indicated * Unwilling/unable to complete surveys electronically
Interventions
- OtherNon-Interventional Study
Non-interventional study
Location
- Mayo Clinic in RochesterRochester, Minnesota