Study of Human Brain-Gut Axis and Gut Microbiome In Patients With Brain Lesions - Repository for Neuroscience Research
Mayo Clinic
Summary
This study explores how microorganisms in the gut can affect the growth and progression of brain tumors.
Description
PRIMARY OBJECTIVES: I. To establish a Mayo Clinic Florida Brain Tumor-Gut Axis Human Biorepository by sequential collection of fecal, urine, blood, saliva, and/or tissue samples and clinical patient information. II. To use spatial transcriptome/proteomics/multi-omics coupled with microbiome data from various sources including brain tissue and stool samples to understand how microbiota could impact disease development, progression, and treatment response in patients with brain cancer. III. To study the effect of microbiome and potential relationships and/or microbiome reconstruction to impac…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * All patients undergoing resection for a tumor of the central nervous system and associated controls are eligible to participate in this study. Exclusion Criteria: * Excluded samples will be from patients younger than 18 years old. There are no exclusions due to race/sex.
Interventions
- OtherNon-Interventional Study
Non-interventional study
Location
- Mayo Clinic in FloridaJacksonville, Florida