Developing a Nutritional Supplement to Increase Collagen Synthesis in People
University of California, Davis
Summary
The purpose of this study is to test whether a natural product supplement can potentiate the increase in collagen synthesis following the ingestion of collagen protein. The investigators have developed a model of natural (GRAS certified) products that stimulate collagen synthesis, in vitro. The investigators will determine whether the natural product supplement can potentiate the collagen synthetic response to the ingestion of collagen protein. Basal and fed serum will be isolated and these samples will be used to treat human engineered ligaments.
Eligibility
- Age range
- 18–30 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Young healthy adults (18-30 y) Exclusion Criteria: * Pregnancy * Smoking * Receiving any medication that may interfere with the study outcomes
Interventions
- Dietary SupplementNatural Product Supplement
Participants will have blood drawn before and one hour after consuming the natural product supplement. For 7-days the participants will perform load-bearing exercise and consume the supplement. On the final day, blood will be collected 4 hours after the final exercise bout.
- Dietary SupplementPlacebo control
Participants will have blood drawn before and one hour after consuming the placebo supplement. For 7-days the participants will perform load-bearing exercise and consume the supplement. On the final day, blood will be collected 4 hours after the final exercise bout.
Location
- Hickey LaboratoryDavis, California