Pulse Oximeter Accuracy in Healthy Humans During Hypoxia
University of California, San Francisco
Summary
The aim of this project is to test the accuracy of pulse oximeters during mild, moderate and severe hypoxia. This is done by comparing the reading of the pulse oximeter during brief, steady state hypoxia with a gold-standard measurement of blood oxygen. This study will be done on healthy male or females between the age group of 18-50.
Description
This study is to determine the accuracy of pulse oximeters, which measure blood oxygen by shining light through fingers, ears or other parts of the body, without requiring blood sampling. The aim of this project is to test the accuracy of pulse oximeters during mild, moderate and severe hypoxia. This is done by comparing the reading of the pulse oximeter during brief, steady state hypoxia with a gold-standard measurement of blood oxyhemoglobin saturation (arterial blood sample processed in a laboratory hemoximeter).The data obtained is submitted by pulse oximeter manufacturers to the FDA for…
Eligibility
- Age range
- 18–50 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: 1. The subject is male or female, aged ≥18 and \<50. 2. The subject is in good general health with no evidence of any medical problems. 3. The subject is fluent in both written and spoken English. 4. The subject has provided informed consent and is willing to comply with the study procedures. Exclusion Criteria: 1. The subject is obese (BMI\>35). 2. The subject has a known history of heart disease, lung disease, kidney or liver disease. 3. Diagnosis of asthma, sleep apnea, or use of CPAP. 4. Subject has diabetes. 5. Subject has a clotting disorder. 6. The subject a hemog…
Interventions
- DeviceControlled desaturation (hypoxemia)
Stable hypoxemia is created in healthy subjects by having them breathe hypoxic air mixtures
Location
- Hypoxia Lab, UCSF Department of Anesthesia and Perioperative CareSan Francisco, California