MIND Foods and Aerobic Training in Black Adults With HTN: An ADRD Prevention Pilot RCT
Indiana University
Summary
The goal of this randomized controlled trial is to determine the impact of Mediterranean-Dash Intervention for Neurodegenerative Delay (MIND) diet and aerobic training on cognition in Black adults with high systolic blood pressure. Researchers will compare Food Delivery and Cooking PLUS Aerobic Training (FoRKS+) versus Enhanced Usual Care (EUC) to evaluate the effects on cognition. Participants will complete cognitive and cardiovascular assessments, 24-hr blood pressure monitoring, standard blood pressure measurements, weight, fingerstick for HbA1c point-of-care testing, and questionnaires. Participants may also choose to participate in an optional blood draw for DNA Repair Capacity testing as a modifiable risk factor for aging-associated diseases.
Description
This randomized controlled trial will evaluate Mediterranean-Dash Intervention for Neurodegenerative Delay (MIND) diet and aerobic training (FoRKS+) versus enhanced usual care (EUC) in Black adults with systolic blood pressure of ≥140 mm Hg. This project seeks to evaluate the potential for high-polyphenol nutritious foods, hands-on training in food management skills, and aerobic exercise to impact cognition and risk factor reduction in persons with prevalent chronic disease. Adults who pass the telephone screen will be invited to complete a blood pressure check for final eligibility determina…
Eligibility
- Age range
- 35–75 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: 1. Fluent in English 2. Marion County resident 3. 35-75 years 4. Self-identified non-Hispanic and Black/African-American/biracial including African-American 5. Systolic BP of ≥140 in prior 12 months from a primary care visit 6. Ability to see and read street signs (self report) 7. Stable housing with independent access to kitchen, including functional stove or hotplate, oven, refrigerator, and freezer (self report) 8. Activity independence per functional activities questionnaire (FAQ; \<3 responses of "Require Assistance" and 0 responses of "Dependent") 9. Normal cognition…
Interventions
- BehavioralEnhanced Usual Care (EUC)
Enhanced Usual Care (EUC) includes 5 weeks of hypertension classes.
- BehavioralFood Delivery and Cooking PLUS Aerobic Training (FoRKS+)
Food Delivery and Cooking PLUS Aerobic Training (FoRKS+) includes 5 weeks of hypertension classes followed by 11 weeks of home-delivered Mediterranean-style ingredient kits and virtual cooking classes, and an additional 12 weeks of aerobic exercise.
Location
- Eskenazi HealthIndianapolis, Indiana