Critical Time Window for Rehabilitation After Incomplete Spinal Cord Injury: Early vs Late Locomotor Training
Milap Sandhu
Summary
The purpose of this study is to evaluate if a specific type of additional walking therapy, called body weight supported treadmill training (BWSTT) affects walking ability following a traumatic spinal cord injury. Specifically, the study will look at whether starting BWSTT, which uses a body harness to support body weight while walking on a treadmill at different times within the first 6 months after the injury, makes a difference in how effective this therapy may be, While we know that the brain re-learns patterns following an injury, there has not been a lot of prior research evaluating how starting this type of walking therapy at specific times within the first 6 months after injury may impact any effectiveness of the additional therapy. The study will randomize participants into four groups: those who start this therapy within 60 days, within 3 months, within 6 months or who do not receive this additional research therapy. Randomization means that which group you will be in as part of this study is determined by chance, like the flip of a coin. The additional walking therapy for this research study, if you are randomized for one of the three groups who receives the additional therapy, will be given on top of (meaning in addition to) any standard of care therapies that you may be receiving at that time point after your injury.
Eligibility
- Age range
- 16–75 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * History of Acute and Traumatic SCI with AIS classification of B, C, or D between the neurological levels of C5 and T12 * Between the ages of 16-74 * Weight bearing as tolerated in bilateral lower extremities * Able to tolerate a harness * Ability to provide informed consent. For minors, consent of parents or primary caregivers/guardians and assent of the minor * Able to provide informed consent within 60 days of injury onset * Able to participate in all study related activities, including 1-year follow up Exclusion Criteria: * Orthopedic injuries, fractures, surgeries,…
Interventions
- ProcedureBody Weight Supported Treadmill Training
For these training sessions, participants will undergo walking training sessions that consist of wearing a harness for either body weight support or as a safety precaution while walking on a treadmill.
Locations (2)
- The Shirley Ryan AbilityLabChicago, Illinois
- Baylor Scott and White Institute for RehabilitationFort Worth, Texas