The American Lung Association (ALA) Deep Phenotyping Ancillary Study of the Lung Health Cohort (LHC)
Johns Hopkins University
Summary
The goal of this observational study is to learn about lung structure and function in a group of 1000 healthy people aged 25 to 35. The main questions it aims to answer are whether people's bodies, environment, and general lung health are associated with: * the structure of the participants lungs' airways, * the structure of blood vessels in the participants lungs and heart, and * the participants lungs' ability to exchange gases. Participants will take four different lung function tests to measure lung function, including: * air movement in the lungs (oscillometry) * lung size (slow vital capacity (SVC) and functional residual capacity (FRC) * gas transfer in the lungs (diffusing capacity for carbon monoxide (DLCO).
Description
The parent Lung Health Cohort (LHC) study will leverage the national infrastructure of the American Lung Association's (ALA) Airways Clinical Research Centers (ACRC) to form the first national cohort of adults focused on respiratory health. The parent LHC study will recruit approximately 4000 community-dwelling adults aged 25-35 from metropolitan regions across the U.S. for the purpose of defining lung health and developing targets to intercept chronic lung disease at its earliest stages. The parent LHC study will be examining a multitude of known and potential factors related to reduced rese…
Eligibility
- Age range
- 25–35 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Age 25-35 years at the time of the baseline examination * Able to read and understand English or Spanish * Has a social security number * Resident (citizen or non-citizen) of the United States (US) for at least 12 months prior to examination. Note: Individuals who are residents of the US who have temporarily spent time living outside of the US during the last 12 months (e.g., student exchange program, military posting) are eligible for participation. * Willing to provide contact information for at least 2 proxies who are likely to know the whereabouts and vital status…
Locations (12)
- University of AlabamaBirmingham, Alabama
- University of California, Los AngelesLos Angeles, California
- National Jewish HealthDenver, Colorado
- Nemours Children's JacksonvilleJacksonville, Florida
- Northwestern UniversityChicago, Illinois
- University of KansasKansas City, Kansas