Transforming Behavioral Healthcare to Improve the Quality of Life for Individuals With Childhood-onset Lupus
Michigan State University
Summary
This study aims to investigate the feasibility and effectiveness of a cognitive behavioral coping skills program, Treatment and Education Approach for Childhood-onset Lupus (TEACH), for youth with cSLE when integrated into medical care. This TEACH program aims to teach participants skills in order to cope with fatigue, pain, and depressive symptoms--symptoms that commonly affect adolescents and young adults with lupus.
Description
Background/Rationale: Childhood-onset systemic lupus erythematosus (cSLE) is a chronic, multisystem, autoimmune disease that disproportionately impacts females of color. It is associated with a more severe disease presentation, and a 20-fold increased risk of mortality compared to adult-onset SLE. Depressive symptoms, anxiety, fatigue, and pain are among the most common presenting complaints which impact health-related quality of life (QOL) in individuals with cSLE. These symptoms are potentially modifiable with behavioral intervention. Our team has created an evidence-based, brief and tailore…
Eligibility
- Age range
- 12–22 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * 1\) be diagnosed with cSLE, meeting the revised American College of Rheumatology Classification Criteria for SLE by age 18 years * 2\) be between the ages of 12 and 22 years * 3\) in recognition of the heterogeneity of cSLE symptoms, have elevations in fatigue (i.e., T scores ≥60; or at least moderate symptoms, on the PROMIS measure) OR depressive symptoms (≥5 on the PHQ-9, T Score ≥ 60 on the BDI or CDI II ), OR pain (i.e., average pain ≥3 out of 10 on the Pain VAS) * 4\) have English language proficiency (their primary caregiver can have English or Spanish language pro…
Interventions
- BehavioralTEACH
TEACH is a cognitive behavioral coping skills program. It consists of six one-hour weekly sessions that are conducted either in-person or remotely.
Locations (7)
- University of Alabama Birmingham HospitalBirmingham, Alabama
- Children's Hospital of New Orleans/ Tulane UniversityNew Orleans, Louisiana
- Helen Devos Children's HospitalGrand Rapids, Michigan
- Montefiore Medical CenterThe Bronx, New York
- Cincinnati Children's Hospital Medical CenterCincinnati, Ohio
- Seattle Children's HospitalSeattle, Washington