eVTE (Electronic Venous Thromboembolism): A Cluster, Randomized, Step-wedge Type II Hybrid Study of an Alert Recommending Extended Duration Thromboprophylaxis for At-risk Discharging Medical Patients to Prevent VTE.
Scott C. Woller, MD
Summary
A new algorithm derived from only patient age and components of the complete blood count and basic metabolic panel can identify patients discharged from the hospital who may benefit from a blood thinner (called rivaroxaban) to decrease their risk of blood clots, and for whom the risk of bleeding is minimal. The purpose of this study is to evaluate the use of a pop-up alert, which will be seen by clinicians when a discharging patient has been identified as being someone for whom the risk of blood clots is high, but for whom bleeding risk is estimated to be low. The pop-up alert will be enabled in a sequential fashion for each group of hospitals in 1 month blocks. We will look to see if the pop-up alert changes the number of patients who receive rivaroxaban. We will also measure the outcomes of blood clots and bleeding among all discharging patients.
Description
The goal of this prospective, cluster, randomized, type II hybrid step wedge, implementation/effectiveness study is to compare the rates of rivaroxaban prescription for extended duration thromboprophylaxis (EDT) in discharging medical patients during the baseline period when no alert informs decision-making to guide EDT, versus EDT prescription during the intervention period when an alert to the discharging clinician is delivered. Grouped sequential hospitals will be introduced to the intervention randomly in a step wedge fashion. Aim 1 is to assess the implementation of the alert to dischar…
Eligibility
- Age range
- 18–110 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Discharging clinician must be in one of the following iCentra electronic health record (Cerner, Kansas City, MO) positions: * Physician, nurse practitioner, or physician assistant hospitalist * Physician internal medicine * Physician family medicine * Patient age ≥ 18 years. * The encounter must be inpatient. * A signed hospital discharge order must be present. * eVTE target population criteria (increased venous thromboembolism risk, low bleeding risk) must be met Exclusion Criteria: * Pregnant during encounter * Discharge order completed by ineligible clinician…
Interventions
- OtherEHR (electronic health record) alert
Pop-up alert that informs the discharging clinician that the patient meets criteria to be considered for extended duration thromboprophylaxis
- OtherNo EHR (electronic health record) alert
During the baseline phase while risk is assessed and stored, no alerting occurs
Location
- Intermountain Medical CenterMurray, Utah