Effect of Raised End-Tidal pCo2 on Choroidal Volume
University of Pittsburgh
Summary
This study is to investigate the relationship between arterial carbon dioxide (CO2) concentration and vitreous pressure on the choroidal volume by integrated intraoperative OCT imaging under eye exams under anesthesia.
Description
Children with normal eyes undergoing an exam under anesthesia or a non-intraocular eye procedure will have one eye examined after research consent is taken. Children have very elastic ocular tissues. When they are having an intraocular procedure positive vitreous pressure can cause the iris to prolapse out of the eye and this can cause intraoperative and postoperative complications. The causes of the positive vitreous pressure have been speculated to be due to an increase in choroidal volume. The Choroid is a layer of blood vessels sitting between the sclera and the retina. Ocular Coherence To…
Eligibility
- Age range
- Up to 8 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * any child undergoing an eye exam under anesthesia for an ophthalmologic reason. * children between the ages newborn to 8 years of age. Exclusion Criteria: * children who are not having an eye exam under anesthesia. * children with a known medical diagnosis that affect the eye to be studied * \* children over the age of 8 years of age. * \* children with altered cerebral autoregulation, increased intracranial pressure, pulmonary hypertension, or any other condition deemed appropriate by the anesthesiologist. * children in whom a laryngeal mask airway will not be used
Interventions
- OtherVentilation manipulation
Effects of ventilation manipulation to achieve desired levels of end tidal carbon dioxide
Location
- University of Pittsburgh Medical CenterPittsburgh, Pennsylvania