The Ontogeny of Fidgety Movements in Infants At High-Risk of Cerebral Palsy
Ann & Robert H Lurie Children's Hospital of Chicago
Summary
The study objective is to improve accuracy in the early detection of neurodevelopmental impairment, especially CP, by evaluating the timepoint (in weeks post term age) that the Prechtl GMA is most useful for prediction of neurodevelopmental impairment at two years of age in children with and without medical complexity. The study team plans to recruit 100 healthy, term-born infants and 250 infants at risk of developing CP for a total of 350 enrolled infants.
Description
Research teams at Northwestern (Prentice), University of Sydney, Fondazione IRCCS Stella Maris, Cerebral Palsy Alliance (CPA) and Murdoch Children's Research Institute (MCRI) will be collecting data in the same manner using the Baby Moves app with the inclusion and exclusion criteria above. The data from the Baby Moves app will be temporarily stored in a common REDcap database at the Murdoch Children's Research Institute (MCRI) with all sites included. The MCRI has all necessary approvals in place to host the videos. Video files from Prentice and Lurie will be transferred to a common REDCap Da…
Eligibility
- Age range
- 0–0 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Infants born full-term with typical development, bithweight \>2500g * Infants with a history of brochopulmonary dysplasia, defined as having a preterm birth (\<33 weeks gestational age) and requiring supplemental oxygen beyond 36 weeks gestational age * Infants with neonatal encephalopathy, who required hypothermic cooling treatment * Infants born \<36 weeks gestational age * Infants born in a multiple gestation pregnancy * Infants with a diagnosis of Trisomy 21 * Infants born and diagnosed with SMA prenatally, via newborn screening assessment or prior to 10 weeks correc…
Interventions
- OtherObservational
Observation of movement patterns through video recordings and neurodevelopmental battery of assessments.
Location
- Feinberg School of Physical Therapy and Human Movement SciencesChicago, Illinois