Virginia Polytechnic Institute and State University
A battery of physiological and behavioral data will be collected before and after application of eTMS. Participants will be veterans or first responders diagnosed with PTSD. Study will be a double-blind, sham-controlled, parallel group, randomized clinical trial.
Veterans and first responders diagnosed with PTSD will be studied to evaluate safety and efficacy of an EEG personalized TMS paradigm. All participants will undergo 2 days of extensive testing prior to eTMS application and 2 days of testing after. Testing will include MRI, OPM, EEG, behavioral tasks, questionnaires, and an EEG sleep study.
Inclusion Criteria: * Veteran or first responder * diagnosed with post-traumatic stress disorder with PCL-5 cutoff of 31 or above Exclusion Criteria: * Claustrophobia * Contraindications to MRI * Pregnant * Uncontrolled medical, psychological, or neurological conditions * Unable to calculate EEG alpha frequency * History of ECT or rTMS * History of intracranial lesion or increased intracranial pressure * History of stroke * History of other neurologic conditions * Family history of epilepsy * Personal history of epilepsy * certain medications
EEG is utilized to determine a personalized frequency to then apply TMS to the frontal lobe.
Arctuva estimate
Verify or correct the compensation shown for this listing.