Massachusetts General Hospital
This research study aims assess whether the Difference Frequency Generation (DFG) laser could be a better alternative to the CO2 laser in terms of reduced side effects and patient downtime.
The primary goal of this study is to compare the pain score and wound healing time in healthy subjects undergoing low fluence fractional ablation using the DFG and CO2 lasers. The secondary objective involves assessing the impact of each laser on dermal vasculature using an Optical Coherence Tomography (OCT) imaging system. Participants will be treated with the DFG and CO2 laser to the upper thighs. Photography, pain scores, and OCT imaging will be recorded over the course of the study visits. The investigators plan to enroll 23 healthy subjects to complete the study. Subjects must be equal…
Inclusion Criteria: * Subjects must be able and willing to provide written informed consent and comply with the requirements of the study protocol; * Subjects must be in good general health, based on answers provided during the screening visit; * Subjects must be able to read and understand English. * Subjects must be above the age of 18. * Subjects must have no history of skin conditions that affect the integrity of the skin barrier. Exclusion Criteria: * Are pregnant or lactating; * Have a history of drug or alcohol abuse or have reported habitual alcohol intake greater than 2 standard dr…
Laser treatment to the upper thigh
Laser treatment to the upper thigh
Angiographic OCT imaging at areas of interest
Arctuva estimate
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