Imaging Pain in a Virtual World: Neuroimaging Biomarkers for Assessing Brain Mechanisms Mediating Virtual Reality Pain Management in Children
Nationwide Children's Hospital
Summary
This study aims to use functional near-infrared spectroscopy (fNIRS) to identify and quantify pain biomarkers during burn dressing changes and pain relief induced by virtual reality (VR).
Description
The objective of this study is to develop central nervous system (CNS) biomarkers of pain experience during inpatient pediatric (age 6-17 years) burn dressing changes and pain relief induced by virtual reality (VR). We plan to use innovative functional near-infrared spectroscopy (fNIRS) to identify and quantify the targeted CNS biomarkers. The ultimate goal of this project is to optimize the CNS biomarkers for predicting and/or monitoring response to VR-based pain reduction approaches for pain management in clinical trials. We will collaborate through a team science model to recruit n=4 pedia…
Eligibility
- Age range
- 6–17 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: 1. Being treated for acute burn injury 2. Age 6-17 years, inclusive 3. Admitted to NCH burn unit for treatment 4. Have a dressing that requires daily changes over 3 days 5. Patient and family caregivers can communicate (read and write) using English Exclusion Criteria: 1. Any wounds that may interfere with study procedures 2. Vision, hearing, or cognitive/motor impairments preventing valid administration of study measures 3. History of motion sickness, seizure disorder, dizziness, or migraine headaches precipitated by visual auras 4. Minors in foster care, prisoners, or…
Interventions
- OtherVR-PAT
Virtual Reality Pain Alleviation Therapy (VR-PAT) played on a Pico Neo 3 Pro Eye device
Location
- Nationwide Children's HospitalColumbus, Ohio