University of South Florida
Intervention for dysgeusia in head and neck cancer patients undergoing radiation therapy. This research proposal aims to investigate potential benefits of mBerry in improving quality of life and nutritional outcome in head and neck cancer patients' post-radiation therapy. Our hypothesis is that cancer patients undergoing radiation therapy will benefit from use of miracle berry in treatment of dysgeusia.
Dysgeusia, characterized by altered taste, is a common side effect of radiation used in oropharyngeal cancer treatment. Radiation affects taste buds, leading to issues like loss of appetite, malnutrition, dependence on feeding tubes, dysphagia, and impacts social and overall quality of life. Patients often report bitter, metallic or no taste with food after radiation. Miracle berries, known for interacting with sweet taste receptors, could potentially transform acidic tastes into sweet ones. The aim is to explore mBerry's potential in alleviating dysgeusia, aiding patients in achieving better…
Inclusion Criteria: * Over 18 years * Diagnosis of mandibular cancer, tonsillar cancer, and lingual cancer * Receiving primary or adjuvant radiation therapy Exclusion Criteria: * Received a total glossectomy or total laryngectomy. * Patients with allergies to peanut, latex, peach, or soy will be excluded as they are at increased risk of allergy to mBerry. * Diagnosis of diabetes as well as prediabetic patients and those that are taking Metformin.
mBerry tablets (.4 grams), which contain protein within the miracle berry called miraculin.
The control group will not received intervention.
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