Zinc and Iron Absorption From Common Beans in Young Adult Women
University of California, Davis
Summary
Fifteen female study participants will be enrolled in a randomized crossover study to measure fractional and total zinc and iron absorption from four common bean (Phaseolus vulgaris) varieties with varying phytate and polyphenolic contents. Phytate, the storage form of phosphorus in plants, and polyphenols, which contribute to the varied colors of common beans, are natural components of the beans and can reduce zinc and iron bioavailability from these foods.
Description
Each participant will attend a total of 10 study visits. The first visit will be a screening visit to determine eligibility, and will include the administration of health history and food frequency questionnaires, and a urine pregnancy test. Participant will also be given a ASA24 24-hour dietary recall at visit 1 to return at visit 2. All subsequent visits (2 through 10) will begin with a blood sample (15 mL, or 1 tablespoon, after a 12 hour overnight fast). Visit 2 will establish the baseline distribution of naturally occurring zinc and iron isotopes in the blood, and will include the admini…
Eligibility
- Age range
- 19–24 years
- Sex
- Female
- Healthy volunteers
- Yes
Inclusion Criteria: * Healthy eumenorrheic (regular monthly menstrual cycles of 25-30-days in length) * BMI 18.5 - 30 kg/m2 * Regular consumer of beans, i.e. ≥ 4 servings per month * Usual iron intake estimated by Food Frequency Questionnaire to be less than the Recommended Daily Allowance (RDA) of 18 mg/d (8) * Subject is willing and able to comply with the study protocols. * Subject is willing to participate in all study procedures. Exclusion Criteria: * Dislike or allergy to beans * Self-reported current or recent pregnancy (within the past 12 months) * Self-reported recent termination o…
Interventions
- OtherSER 118
Bean High in Phytic Acid and High in Inhibitory Polyphenols
- OtherLMP 1001
Bean Low in Phytic Acid and High in Inhibitory Polyphenols
- OtherLPA 586
Bean Low in Phytic Acid and Low in Inhibitory Polyphenols
- OtherKAT B1
Bean High in Phytic Acid and Low in Inhibitory Polyphenols
Location
- Department of NutritionDavis, California