Positive Psychology Intervention for Hematopoietic Stem Cell Transplantation Survivors
Brigham and Women's Hospital
Summary
This randomized clinical trial is evaluating the impact of a positive psychology intervention (PATH) on anxiety symptoms, depression symptoms, and quality of life in survivors of hematopoietic stem cell transplant (HSCT) compared to usual care.
Description
Patients undergoing hematopoietic stem cell transplantation (HSCT) deal with numerous physical and psychological symptoms during acute hospitalization and recovery. Of the few psychosocial interventions tailored to the needs of the HSCT population, most focus on the needs of patients in the pre-transplant phase or during the HSCT hospitalization, but not during the acute recovery period starting at 100-days post-HSCT. Hence, the investigators developed a remotely-delivered positive psychology intervention, Positive Affect in the Transplantation of Hematopoietic Stem Cells (PATH). This interven…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Adult patients (aged 18 years and older) undergoing allogeneic HSCT and are approaching 100-days post-HSCT * Ability to speak, read, and respond to questions in English or Spanish to complete study procedures * Access to a basic telephone Exclusion Criteria: * Patients who underwent allogeneic HSCT for benign hematologic conditions * Patients with severe psychiatric or cognitive conditions, such as dementia, determined by their transplant oncologist to make them unable to provide informed consent or comply with study procedures
Interventions
- BehavioralPATH
PATH, a phone-delivered positive psychology intervention for patients who have undergone HSCT, consists of three 3-week modules. The first module focuses on gratitude and physical activity goal setting. The second module focuses on personal strengths and resources to enhance daily physical activity. The third module focuses on meaning and assessing barriers to physical activity. The third week of each module is an integration exercise dedicated to help participants explore practical ways of incorporating the themes for the given module into daily life. A trained interventionist will guide participants to complete each 30-minute weekly session.
Locations (3)
- Moffitt Cancer CenterTampa, Florida
- Dana Farber Cancer InstituteBoston, Massachusetts
- Duke Cancer InstituteDurham, North Carolina