Wound Irrigation With Saline Versus Hypodilute-chlorhexidine After Cesarean Section: a Randomized Clinical Trial (WISHES Study)
Loma Linda University
Summary
This investigator-initiated, open-label, randomized controlled trial will explore the effects of two treatment arms, comparing standard treatment with normal saline against Irrisept, a jet lavage solution containing a low concentration of Chlorhexidine Gluconate (CHG) at 0.05% in 99.95% sterile water for irrigation. The study aims to evaluate the impact on postoperative wound healing in patients who have undergone cesarean delivery.
Eligibility
- Age range
- 18+ years
- Sex
- Female
- Healthy volunteers
- No
Inclusion Criteria: * Age 18 or older * Singleton pregnancy * Planned cesarean delivery at gestational age 37 weeks or later at Loma Linda University Children's Hospital * Planned post-operative follow up with Loma Linda OBGYN * Speak English or Spanish * At least one of the following medical complications: Obesity BMI\>= 30kg/m2, Diabetes, Spontaneous rupture of membranes, Intraamniotic infection Exclusion Criteria: * Emergency cesarean delivery
Interventions
- DeviceIrrisept
450ml low concentration (0.05%) Chlorhexidine Gluconate (CHG) in 99.95% Sterile Water
- DrugNormal Saline
450mL
Location
- Loma Linda UniversityLoma Linda, California