Health Effects of Grain Foods in Adults
Purdue University
Summary
This study will assess the effects of eating whole grain foods versus refined grain foods with different amounts of added sugar. It is hypothesized that a diet including grain products will have beneficial effects on taste hedonics, appetite, food/energy intake, body weight, blood pressure, acute and chronic glycemia and acute and chronic lipemia compared to customary diets controlling for added sugars, saturated fats and sodium.
Description
This 16-week, randomized, controlled, parallel-arm, clinical trial will assess the effects of consuming four different categories of grain foods on taste hedonics, appetite, food/energy intake, body weight, and blood pressure as well as acute and longer-term glycemia and lipemia. It will also examine the effects of foods varying in grain/carbohydrate composition on the microbiome and microbiota functionality. One hundred and twenty adults will be recruited and randomly assigned to one of four intervention groups. These groups will be defined by the diets they are prescribed. All will be prescr…
Eligibility
- Age range
- 21–60 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * male and female; 21 to 60 years old; Hemoglobin A1c concentration between 5.7 and 6.4% * Prefer no use of medications, but if on medication, must have been on a stable dose for 3 months and plan to remain at the same dose for the duration of the trial. * low customary intake of whole grain foods (less than 2 servings per day) and high energy from added sugar (greater than 10% energy). Exclusion Criteria: * Grain or dairy sensitivities or allergies or celiac disease; sensitivity or allergy to other foods that would result in refusal to eat a class of foods. * smoker * i…
Interventions
- OtherHigh Whole Grain, Low Sugar
6 servings of whole grain and \<13% energy from added sugars.
- OtherLow Whole Grain, Low Sugar
3 servings of whole grain and \<13% energy from added sugars.
- OtherHigh Whole Grain, High Sugar
6 servings of whole grain and \>13% energy from added sugars.
- OtherLow Whole Grain, High Sugar
3 servings of whole grain and \>13% energy from added sugars.
Location
- Purdue UniversityWest Lafayette, Indiana