Sleep and Emotion Processing in Adolescent Post-Traumatic Stress Disorder
University of Wisconsin, Madison
Summary
The goal of this clinical trial is to characterize the role of sleep, emotion processing, and daily affect in post-traumatic stress disorder (PTSD) and whether improving sleep quality using slow wave activity enhancement will impact next-day affect in youth. Participants will attend 4 study visits: * A clinical and trauma assessment visit * A testing day that may include cognitive testing, surveys, and an MRI. * An overnight sleep study following one week of at-home sleep recordings with the device in the sham condition * An overnight sleep study following one week of at-home sleep recordings with the device in the sleep enhancement condition
Description
In this study, researchers aim to characterize sleep and explore its relationship to emotion processing and daily affect in 165 youth spilt into 3 groups. Researchers will use advanced sleep assessment methodologies including: (1) high-density EEG (256 channels) in the laboratory to explore the regional distribution of sleep before and after an emotional learning task and; (2) a sleep-wearable EEG recording headband, SmartSleep, to record sleep longitudinally at home. Using SmartSleep's sleep enhancement algorithms, researchers will determine whether the deepest sleep, slow-wave activity (SWA)…
Eligibility
- Age range
- 15–18 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: All participants must meet all of the following criteria: * Aged 15-18 years old, inclusive * Must agree to inform the investigators within 48 hours of any emergent medical conditions and procedures * Able to lie still on their back for up to 1 hour * Must not be pregnant * Must agree not to participate in any other interventional clinical trials during the duration of the study * Must be willing to comply with all study procedures * Agree to have study visits video and/or audio recorded, including consent visit, clinical assessments (for staff training) and in-laboratory…
Interventions
- DeviceSmartSleep device
Device worn during sleep
Location
- University of WisconsinMadison, Wisconsin