Neuronavigated Non-invasive Brain Stimulation for Nicotine Dependence.
University of Missouri-Columbia
Summary
The purpose of the study is to examine the effects of continuous theta burst stimulation (cTBS) on different forms of cognitive control in adults who smoke cigarettes, and to determine if the location where cTBS is delivered may help smokers reduce or quit smoking. Participation in the study will take 3-weeks over 4 visits, with a total time commitment of approximately 12 hours.
Eligibility
- Age range
- 18–60 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: 1. Nicotine Dependence as measured by: Smoke ≥ 8 cigarettes/day for ≥ 2 yrs, expired carbon monoxide (CO) concentration of ≥ 10 ppm, positive urine cotinine test and FTND score ≥ 3 Or ≥ 15 uses of electronic cigarette/day for ≥ 1 year, positive urine cotinine test, and PS-ECDI score ≥ 3 2. English Fluency 3. Functional Vision (with corrective lenses as needed) Exclusion Criteria: 1. Use of psychotropic and antiepileptic medications in the last month 2. Presence of an untreated illness or serious medical condition 3. History of major neurological illness 4. Contraindicati…
Interventions
- DeviceRepetitive Transcranial Magnetic Stimulation (rTMS)
Continuous theta burst rTMS
Location
- Health Neuroscience CenterColumbia, Missouri