Adolescent Outcomes of Post-operative Opioid EXposure
Sharon Levy
Summary
The goal of this observational study is to examine the factors associated with the transition from medical exposure to opioids with "signposts" of future opioid use disorder among adolescent surgical patients. The main question aims to identify factors (moderators, mediators, and covariates) associated with risk factors for opioid use disorder (ROUD) in the 12 months following major surgery with opioid exposure among adolescents aged 12-17. Participants will be asked to complete electronic surveys pre- and post-operatively and approve the collection of peri-operative data from the Electronic Medical Record to assess correlations.
Description
This project will collect data from a diverse sample of 10,000 dyads, including adolescent (aged 12-17 years, inclusive) patients undergoing major surgery with planned post-operative opioid analgesic use. and a parent (Total N=20,000) to identify ROUD that may occur within the 12 months after surgery. The resulting data repository will allow clinician scientists and physicians to develop research-informed pain management protocols for adolescent surgical patients to reduce the risk of OUD in this vulnerable population. Using a novel combination of data sources (electronic medical records (EMR…
Eligibility
- Age range
- 12–17 years
- Sex
- All
- Healthy volunteers
- No
Adolescent Inclusion Criteria 1. Adolescents between the ages of 12 to 17 years old, inclusive, who are scheduled to undergo a scheduled surgical procedure with a greater than 90% likelihood of requiring opioid analgesia for at least 48 hours post-operatively (as an inpatient) or discharged home with at least a 48-hour supply of prescription opioids. • Opioid prescribing practices vary by institution; therefore, eligible surgical procedures will be determined on a site-by-site basis. 2. Adolescents willing and able to provide informed assent and have a parent/caregiver willing to provide…
Locations (5)
- Children's Hospital ColoradoAurora, Colorado
- Johns Hopkins All Children's HospitalSt. Petersburg, Florida
- Boston Childrens Hopsital - Division of Addiction MedicineBoston, Massachusetts
- Cincinnati Children's Hospital Medical CenterCincinnati, Ohio
- Children's Hospital of PhiladelphiaPhiladelphia, Pennsylvania