The Foods & Oil to Repair, Correct and Enhance Strength (FORCES) Study: Determining the Effect of Dietary Oils on Muscle Function, Strength and Mass
Ohio State University
Summary
The proposed research is a parallel arm, randomized placebo-controlled clinical trial designed to assess changes in muscle strength, volume, fatigue resistance, and mobility in older adults after daily consumption of 12g of linoleic acid-rich oil.
Description
Study Objectives 1. To assess the effect of linoleic acid supplementation on muscle strength, muscle volume, fatigue- resistance, and physical mobility. 2. To quantify the impact of linoleic acid supplementation on cardiolipin species and mitochondrial function in skeletal muscle of older adults
Eligibility
- Age range
- 65–80 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Linoleic Acid Intake \<75% of the adequate intake * Probable sarcopenia Exclusion Criteria: * Gastrointestinal diseases or disorders (including pancreatic and gastric bypass surgery) where consumption of the study foods would be contraindication or where the disease or disorder could negatively affect nutrient absorption and/or would prevent participants from tolerating the study foods * Hyperthyroidism diagnosis * Food Allergy or intolerances * Any dietary restriction where consumption of the study foods or any ingredient would be contraindicated * Unstable management…
Interventions
- OtherHigh Linoleic Acid Foods
Two food products containing 6g of high linoleic safflower oil each will be consumed each day for a total of 12g daily
- OtherHigh Oleic Acid Foods
Two food products containing 6g of high oleic safflower oil each will be consumed each day for a total of 12g daily
Location
- The Ohio State UniversityColumbus, Ohio