Facilitating Neuroplastic Changes of Acute Stroke Survivors With Severe Hemiplegia
University of Maryland, Baltimore
Summary
This project will develop a wearable rehabilitation robot suitable for in-bed acute stage rehabilitation. It involves robot-guided motor relearning, passive and active motor-sensory rehabilitation early in the acute stage post-stroke including patients who are paralyzed with no motor output. The early acute stroke rehabilitation device will be evaluated in this clinical trial.
Description
Stroke survivors often experience loss of motor control and impaired function. Immediately after stroke, there is a time-limited window of heightened plasticity during which the greatest gains in recovery occur. Therefore, early intensive sensorimotor rehabilitation post-stroke is critical in improving functional outcomes and minimizing disability. However, acute stroke survivors often receive little active training to improve mobility during their hospital stay and they are left alone during most of the day. Especially for those acute patients with no voluntary motor output, active motor trai…
Eligibility
- Age range
- 30–85 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Acute first time unilateral hemispheric stroke (hemorrhagic or ischemic stroke, 24 hours after admission to 1 month post-stroke at the start of the proposed treatment) * Hemiplegia or hemiparesis * 0≤Manual Muscle Testing (MMT)\<=2 * Age 30-85 * Ankle impairments including stiff calf muscles and/or inadequate dorsiflexion Exclusion Criteria: * Medically not stable * Associated acute medical illness that interferes with ability to training and exercise * No impairment or very mild ankle impairment of ankle * Severe cardiovascular problems that interfere with ability to…
Interventions
- DeviceMotor relearning training
Ankle motor control relearning training under real-time feedback
- DevicePassive stretching
Passive stretching under intelligent robotic control
- DeviceGamed-based active movement training
Active movement training through movement games with robotic assistance
- DevicePassive movement
Passive movement in the joint middle range of motion
- DeviceActive movement training
Active movement training without robotic assistance
- DeviceAnkle torque and motion measurement
Ankle torque and motion measurement with no real-time feedback
Locations (2)
- University of Maryland BaltimoreBaltimore, Maryland
- UMROIBaltimore, Maryland