Mayo Clinic
Adults who gain most of their excess weight in the abdominal area typically do not respond to factors that "turn on" fat cells the same way as people who don't have excessive weight. Researchers are trying to understand why fat tissue responds differently in people with different body types.
Inclusion Criteria: * Males and females between 18 and 65 years of age who are able to comprehend instructions, follow study procedures, willing to sign an informed consent form, and consume an isoenergetic diet eating all meals from Mayo Clinical Research and Trials Unit for at least 3 days prior to study. * Overweight/Obese volunteers will have a BMI 29.0 - 40.0 kg/m2 o Upper body/visceral obesity (UBO) in women will be defined as those with a waist-hip ratio (WHR) \> 0.85 and/or increased visceral fat by single slice CT scan, usually with \> 120 cm2 of visceral fat by CT scanning or a v…
Intravenous infusion 200 ug/hr for 2 hours, 100 ug/hr for 30 minutes
Intravenous infusion
Arctuva estimate
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