Polyethylene Wear Particle Analysis of Total Hip Arthroplasty -International Multicenter Study-
Osaka Metropolitan University
Summary
Purpose of research The purpose of this study was to demonstrate that polyethylene (Vitamin E-containing polyethylene), a newly introduced biomaterial for tibial inserts in hip replacement surgery and widely used clinically, but whose mid- to long-term clinical results are still unknown, is superior to conventional polyethylene in vivo. The aim of this project is to conduct an international multi-center joint research study to determine whether polyethylene wear debris production can be reduced in the future, using an in vivo polyethylene wear debris analysis method that the investigators developed as a method that can provide early feedback.
Description
Research method In this study, the investigators conducted the following steps to determine the in vivo wear particles (number, size, and morphology) of conventional polyethylene, whose long-term results have already been clarified, and vitamin E-containing polyethylene, whose mid- to long-term results have not yet been clarified. Clarifying the difference. Target of this research In this study, the investigators will focus on patients undergoing revision hip arthroplasty as a routine medical treatment. First total joint replacement * 30 patients using polyethylene containing Vitamin E * 30…
Eligibility
- Age range
- 20+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: 1. Patients undergoing revision hip arthroplasty within the study period 2. Patients over 20 years old 3. Patients who have received a sufficient explanation, have sufficient understanding, and have given their free written consent. 4. Patients who have passed 2 years or more since their first total hip arthroplasty Exclusion Criteria: 1\. Patients who are judged to be unsuitable as research subjects by the research physician
Interventions
- Devicepolyethylene
No intervention as this is an observational study
Locations (2)
- Mayo ClinicRochester, Minnesota
- Osaka Metropolitan UniversityOsaka