Effects of Lean Beef Consumption on Cardiometabolic Health and Gut Microbiome
University of Missouri-Columbia
Summary
This study is investigating the benefits of lean beef consumption on cardiometabolic health and gut microbiome.
Description
The study is a 6-wk randomized, controlled, and parallel arm clinical trial. Participants will be randomized to consume either lean grain-fed beef, lean grass-fed beef, or plant-based meat for 6 weeks. Outcomes assessed will include metabolic, inflammatory, and gut microbiome markers.
Eligibility
- Age range
- 18–45 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Age: 18-45 years of age * BMI: 18-35 kg/m2 * Willingness to consume study foods. * Willing to comply with study protocol. * Consistent diet and activity patterns for 4 weeks * Weight stable (≤5 kg change over the last 3 months) * Non-smoker \>1 year or more Exclusion Criteria: * Allergies to foods provided in the study * Diabetes * Gastrointestinal disease and/or bariatric surgery * Uncontrolled hypertension and blood pressure ≥ 180/110 * Illicit drug use * Recent consumption of antibiotics or probiotics * Recent start of medications that affect metabolism or appetite.…
Interventions
- OtherLean (≥90%) Grass-Fed Beef
The specified amount will be 4 oz. per day or 28 ounces per week for participants with an energy requirement of 2000 kcal.
- OtherLean (≥90%) Grain-Fed Beef
The specified amount will be 4 oz. per day or 28 ounces per week for participants with an energy requirement of 2000 kcal.
- OtherPlant-Based Meat
Plant-based meat would be macronutrient matched to the same quantities of meat prescribed for a given energy level.
Location
- University of Missouri-ColumbiaColumbia, Missouri