Prospective Evaluation of Disparities in Provision of Allogeneic Transplantation
M.D. Anderson Cancer Center
Summary
To look at the effect of a recipient's ancestry and socio-economic status on their choice of bone marrow transplantation donor cells and their chance of receiving genetically similar (allogeneic) bone marrow cells versus cells that are not genetically similar (allograft).
Description
Primary Objectives To prospectively evaluate graft options and choice of donor by patient ancestry and SES for allograft candidates at MDACC. Secondary Objectives * To prospectively evaluate time to transplant for allograft candidates at MDACC. * To evaluate treatment-related mortality for allograft candidates at MDACC. * To assess overall survival for allograft candidates at MDACC. * To prospectively evaluate receipt of preferred unrelated donor for allograft recipients at MDACC. * To evaluate receipt of an optimal graft for allograft recipients at MDACC.
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: 1. ≥ 18 years of age. 2. Candidate for allogeneic transplantation Exclusion Criteria: 1\) Allogeneic stem cell transplantation not medically indicated.
Interventions
- BehavioralPatient Ancestry Questionnaires
Participants will be asked to complete a demographics and ancestry questionnaire at the baseline visit before you and your doctor select bone marrow donation candidates.
Location
- MD Anderson Cancer CenterHouston, Texas