Promoting Neuroplastic Changes of Patients With TBI
University of Maryland, Baltimore
Summary
This project will develop a wearable rehabilitation robot suitable for in-bed acute stage rehabilitation. It involves robot-guided motor relearning, passive and active motor-sensory rehabilitation early in the acute stage post-TBI including patients who are paralyzed with no motor output. The early acute TBI rehabilitation device will be evaluated in this clinical trial.
Description
Early after TBI, patients often have significant sensorimotor impairment. There is heightened neural excitability, which may be used to facilitate recovery in the acute phase post stroke. However, there has been a lack of effective and practical protocols and devices for early intensive sensorimotor therapy. The proposed randomized clinical trial using a wearable rehabilitation robot, muscle electromyography (EMG), and/or potentially brain electroencephalogram (EEG) signal seeks to provide early intensive sensorimotor training facilitated by real-time audiovisual and haptic feedback, intellige…
Eligibility
- Age range
- 30–85 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Acute first time unilateral hemispheric stroke (hemorrhagic or ischemic stroke, 24 hours after admission to 1 month post-stroke at the start of the proposed treatment) * Hemiplegia or hemiparesis * 0≤Manual Muscle Testing (MMT)\<=2 * Age 30-85 * Ankle impairments including stiff calf muscles and/or inadequate dorsiflexion Exclusion Criteria: * Medically not stable * Associated acute medical illness that interferes with ability to training and exercise * No impairment or very mild ankle impairment of ankle * Severe cardiovascular problems that interfere with ability to…
Interventions
- DeviceMotor relearning training with wearable ankle robot
Ankle motor control relearning training under real-time feedback
- DevicePassive stretching with wearable ankle robot
Passive stretching under intelligent robotic control
- DeviceGamed-based active movement training with wearable ankle robot
Active movement training through movement games with robotic assistance
- DevicePassive movement with limited wearable ankle robot
Passive movement in the joint middle range of motion
- DeviceActive movement training with limited wearable ankle robot
Active movement training without robotic assistance
- Device
Location
- Li-Qun ZhangBaltimore, Maryland