Mapping of Electrical Properties in the Brain.
Mayo Clinic
Summary
This study evaluates imaging methods for monitoring neural and electrical activity in the brain for improving clinical diagnosis.
Description
PRIMARY OBJECTIVES: I. Optimize pulse sequence acquisitions for diffusion imaging on clinical MRI vendor systems. II. Develop image-based MRI models (including diffusion-based MRI) that accurately depict the multi-regional electrical properties in the brain (e.g., resistivity, current) to inform of neural integrity and function (including white matter tract integrity) in diseased and non-diseased states. III. Compare/correlate image-based MRI models (e.g., diffusion) with existing structural, physiologic, and functional MRI methods (e.g., tensor imaging, fMRI, DSC-MRI, etc). IV. Further tr…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Aim 1: normal healthy volunteers * Aim 2, 3, 4: participants included in IRB 16-002424, including those that have undergone surgical biopsy/resection for suspected or known glioma Exclusion Criteria: * Healthy volunteer unable to have an MRI
Interventions
- OtherNon-Interventional Study
Non-interventional study
Location
- Mayo Clinic in ArizonaScottsdale, Arizona