CAUSAL: Cohort to Augment the Understanding of Sarcoma Survivorship Across the Lifespan

Vanderbilt-Ingram Cancer Center

Summary

This study evaluates the impact that a sarcoma diagnosis and treatment have had on patients over time.

Description

* To evaluate the incidence and prevalence and the impact of disease, treatment, sociodemographic and lifestyle contributors on adverse oncologic outcomes (lack of response, recurrence) and non- oncologic outcomes (physical and psychosocial function, financial toxicity, short and long-term organ toxicity) and mortality in the cohort. * To evaluate the role of drug metabolism and DNA repair genes via functional polymorphisms, known toxicity associated polymorphisms and genetically predicted gene expression levels, as well as polygenic risk scores, on treatment efficacy, cancer therapy-induced n…

Eligibility

Age range: Not specified
Sex: All
Healthy volunteers: Yes

Detailed criteria

Patients at any age with a history of sarcoma, with or without evidence of a persistent disease • For pediatric patients * Parent/primary caregiver of patient * Sibling of patient aged 8 years or older

Interventions

Other
Surveys
Complete surveys
Other
Blood Collection
Undergo blood collection
Other
Saliva Collection
Undergo salvia collection
Other
Urine Collection
Undergo urine collection
Other
Stool Collection
Undergo stool collection
Other
Tissue collection
Undergo tissue collection
Other
Physical Activity Monitoring
FitBit will be worn to track physical activity

Location

Vanderbilt University/Ingram Cancer Center
Nashville, Tennessee
cip@vumc.org 800-811-8480

CAUSAL: Cohort to Augment the Understanding of Sarcoma Survivorship Across the Lifespan

Summary

Description

Eligibility

Interventions

Location

Compensation

Run this study?

Details

Conditions