Light vs. Moderate Intensity Exercise in Individuals With Myasthenia Gravis
HealthPartners Institute
Summary
The overall purpose of this pilot study is to examine the feasibility, acceptability, and tolerability of light and moderate intensity exercise in adults with MGeffect of light vs. moderate intensity exercise on health outcomes. Participants will be enrolled into the NeuroWell exercise program, which is geared toward individuals with neurological disorders or injuries and led by Certified Exercise Physiologists (CEPs) at the HealthPartners Neuroscience Center. A total of 20 people with MG will be enrolled in this study and participate in a small group exercise program 3 times a week for 12 weeks. Participants will be randomized into two exercise groups: 1) Light intensity or 2) Moderate intensity. We hypothesize that light and moderate intensity exercise will be feasible, acceptable, and tolerable in adults with MG and that individuals in the light intensity exercise group will be able to achieve the same improvement in health outcomes as the moderate intensity group.
Eligibility
- Age range
- 18–80 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Ability to provide and provision of signed and dated informed consent form. * Age 18-80 * Diagnosis of generalized MG. * On a stable MG prescription medication regimen for the last 3 months. Exclusion Criteria: * Non-English speaking * Regular exercise participation within the month prior to study enrollment or any outside exercise participation during the study intervention period. * Significant cognitive impairment of any etiology that would impact study participation. * History of heart failure, chronic lung disease, angina or any other condition that causes unreaso…
Interventions
- BehavioralLight Intensity Exercise
12 weeks light intensity strength and endurance NeuroWell exercise program, specifically developed for individuals with neurological disorders or injuries. Participants have the intensity goals descripted in the experimental arm.
- BehavioralModerate Intensity Exercise
12 weeks moderate intensity strength and endurance NeuroWell exercise program, specifically developed for individuals with neurological disorders or injuries. Participants have the intensity goals descripted in the experimental arm.
Location
- HealthPartners Neuroscience CenterSaint Paul, Minnesota