Sleep Promoting Intervention to Improve Diabetes Outcomes and Executive Function in Adolescents With T1D
Vanderbilt University Medical Center
Summary
The goal of this work is to conduct a randomized trial evaluating the effects of a behavioral intervention to increase sleep duration and quality for adolescents with type 1 diabetes (T1D). The impact of the sleep-promoting intervention on executive function and glycemic outcomes will be assessed. We will also explore multiple components of the recently identified central nervous system glymphatic system and evaluate how these components change and impact brain integrity and function with improved sleep.
Description
This randomized controlled trial will assess whether a behavioral coaching intervention to improve sleep duration and quality in adolescents with type 1 diabetes will improve glucose control and executive function. We will recruit a sample of 150 adolescents with type 1 diabetes (T1D) and their caregivers at a single medical center. We plan to recruit equal numbers of boys and girls and over-enroll youth from minoritized racial and ethnic groups. After obtaining informed consent/assent and baseline data, we will randomize adolescents to the Sleep Coach condition (n=75) or the Enhanced Usual Ca…
Eligibility
- Age range
- 11–17 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * 11-17 years of age at the time of enrollment * Diagnosed with type 1 diabetes for ≥ 12 months * Report insufficient sleep (\< 8 hrs./night for 13-17 year-olds, \<9 hrs./night for 11-12 year-olds) but have no other sleep disorders or sleep apnea * Are not meeting the target for HbA1c (\<7%) * Able to read /speak English Exclusion Criteria: * Participant has other serious health conditions that interfere with diabetes management * Optional MRI portion of the study - anything that would prevent an adolescent from receiving a high-quality MRI of the brain (metal implants o…
Interventions
- BehavioralSleep Coach
Sleep-promoting intervention consisting of 4 phone sessions to improve sleep duration and consistency.
- BehavioralDiabetes Education
Participants will receive a a binder with educational information about diabetes and educational messages from the study team.
Location
- Vanderbilt University Medical CenterNashville, Tennessee